Clinical Trial Manager | End-to-End Study Oversight
Salary: £55,000 – £75,000 per year (depending on experience)
Location: London or Manchester (Hybrid – 2–3 days onsite per week)
Type: Full-Time
Job Category: Biotechnology
Industry: Healthcare Technology / Clinical Trials / Biotechnology
Job Owner: Tariq Masood
Job Description
We are hiring a highly experienced and proactive Clinical Trial Manager (CTM) to lead and manage full-cycle clinical trial operations.
In this role, you will oversee the planning, initiation, execution, and closeout of Phase I–IV clinical trials across diverse therapeutic areas — ensuring strict compliance with ICH-GCP, MHRA, and sponsor guidelines.
You’ll serve as a strategic point of contact for internal teams, CROs, clinical sites, and vendors, ensuring the delivery of high-quality clinical trials on time and within budget.
This is an outstanding opportunity for a skilled professional seeking to advance their leadership career in clinical research management.
Experience
Minimum 5+ years in clinical operations, with at least 2 years in a CTM or study lead role.
Key Responsibilities
- Oversee clinical trial planning and implementation from protocol development through final study report.
- Lead cross-functional teams (CRA, Data Management, Regulatory, Biostatistics) and manage CRO oversight.
- Develop and manage study budgets, timelines, and site selection activities.
- Monitor trial metrics, implement risk mitigation plans, and evaluate vendor performance.
- Ensure regulatory compliance with ICH-GCP, EMA, MHRA, and FDA standards.
- Serve as the primary point of contact for clinical sites, investigators, and key stakeholders.
- Coordinate and lead internal/external meetings, progress updates, and reports.
- Maintain Trial Master Files (TMF) to inspection-ready standards.
Required Skills
- Strong understanding of clinical trial regulations, GCP, ICH, and MHRA requirements.
- Proven experience managing global or multi-site clinical studies.
- Excellent leadership, team coordination, and stakeholder management skills.
- Strong command of budget management and vendor oversight.
- Proficient with EDC systems, CTMS, and Microsoft Office tools.
Desired Skills
- Degree in Life Sciences, Health Sciences, or equivalent (BSc, MSc).
- Professional certifications such as ACRP, SOCRA, or equivalent.
- Experience in oncology, rare disease, or CNS clinical trials.
- Familiarity with EU CTR and decentralized trial models.
Job Benefits
- Competitive salary with performance-based bonus
- Private medical insurance & pension scheme
- Clear career development pathway with leadership training
- Flexible hybrid working (2–3 days office-based)
- Opportunity to manage global, multi-centre clinical trials
Education
- Bachelor’s degree required; Master’s or clinical qualification preferred.
Additional Details
- Experience Required: Minimum 5 years in clinical research, including 2+ as CTM or Lead CRA
- Sponsorship: Not considered
